Yang, K., Essa, A., Noriega, D., Yu, D., Osiecki, L., Gauvin, C. A., Illmann, C., Bortolato, M., Dunn, E. C., Mathews, C. A., & Scharf, J. M. (2022). Relationship between adverse childhood experiences and symptom severity in adult men with Tourette Syndrome. Journal of Psychiatric Research, 155, 252–259. https://doi.org/10.1016/j.jpsychires.2022.08.024
Abdallah, S. B., Realbuto, E., Kaka, M. O., Yang, K., Topaloudi, A., Paschou, P., Scharf, J. M., & Fernandez, T. V. (2022). The genetic basis of Gilles de la Tourette syndrome. International Review of Movement Disorders. https://doi.org/10.1016/bs.irmvd.2022.07.001
Claudio-Campos K, Stevens D, Koo SW, Valko A, Bienvenu OJ, Budman CB, Cath DC, Darrow S, Geller D, Goes FS, Grados MA, Greenberg BD, Greenberg E, Hirschtritt ME, Illmann C, Ivankovic F, King RA, Knowles JA, Krasnow J, Lee PC, Lyon GJ, McCracken JT, Robertson MM, Osiecki L, Riddle MA, Rouleau G, Sandor P, Nestadt G, Samuels J, Scharf JM, Mathews CA. Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome? Movement Disorders. 2021 Aug;36(8):1899-1910.
Abdulkadir M, Yu D, Osiecki L, King RA, Fernandez TV, Brown LW, Cheon KA, Coffey BJ, Garcia-Delgar B, Gilbert DL, Grice DE, Hagstrøm J, Hedderly T, Heyman I, Hong HJ, Huyser C, Ibanez-Gomez L, Kim YK, Kim YS, Koh YJ, Kook S, Kuperman S, Leventhal B, Madruga-Garrido M, Maras A, Mir P, Morer A, Münchau A, Plessen KJ, Roessner V, Shin EY, Song DH, Song J, Visscher F, Zinner SH, Mathews CA, Scharf JM, Tischfield JA, Heiman GA, Dietrich A, Hoekstra PJ. Investigation of gene-environment interactions in relation to tic severity. J Neural Transmission (Vienna). 2021 Nov; 128 (11): 1757-1765.
Tsetsos F, Yu D, Sul JH, Huang AY, Mathews CA, Scharf JM, Paschou P. Synaptic processes and immune-related pathways implicated in Tourette syndrome. Translational Psychiatry. 2021 Jan 18;11(1):56.
Zhou D, Yu D, Scharf JM, Mathews CA, McGrath L, Cook E, Lee SH, Davis LK, Gamazon ER. Contextualizing genetic risk score for disease screening and rare variant discovery. Nature Communications. 2021 Jul 20;12(1):4418.
Halvorsen M, Szatkiewicz J, Mudgal P, Yu D, Psychiatric Genomics Consortium TS/OCD Working Group, Nordsletten AE, Mataix-Cols D, Mathews CA, Scharf JM, Mattheisen M, Robertson MM, McQuillin A, Crowley JJ. Elevated common variant genetic risk for Tourette syndrome in a densely-affected pedigree. Molecular Psychiatry. 2021 Sep 15.
Grant JE, Peris TS, Ricketts EJ, Lochner C, Stein DJ, Stochl J, Chamberlain SR, Scharf JM, Dougherty DD, Woods DW, Piacentini J, Keuthen NJ. Identifying subtypes of trichotillomania (hair pulling disorder) and excoriation (skin picking) disorder using mixture modeling in a multicenter sample. J Psychiatric Research. 2020 Nov 4:S0022-3956(20)31057-8.doi: 10.1016/j.jpsychires.2020.11.001. Online ahead of print.
Bralten J, Widomska J, Witte W, Yu D, Mathews CA, Scharf JM, Buitelaar J, Crosbie J, Schachar R, Arnold P, Lemire M, Burton CL, Franke B, Poelmans G. Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling. Translational Psychiatry. 2020 Apr 27;10(1):121.doi: 10.1038/s41398-020-0793-y.
Cross-Disorder Group of the Psychiatric Genomics Consortium (including Scharf JM). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.Cell. 2019 Dec 12; 179(7):1469-1482. doi: 10.1016/j.cell.2019.11.020.
Mufford M, Cheung J, Jahanshad N, van der Merwe C, Ding L, Groenewold N, Koen N, Chimusa ER, Dalvie S, Ramesar R, Knowles JA, Lochner C, Hibar DP, Paschou P, van den Heuvel OA, Medland SE, Scharf JM, Mathews CA, Thompson PM, Stein DJ and the Psychiatric Genomics Consortium Tourette Syndrome Working Group. Concordance of genetic variation that increases risk for tourette syndrome and that influences its underlying neurocircuitry. Translational Psychiatry. 2019 Mar 22; 9(1):120. doi: 10.1038/s41398-019-0452-3.
Yu D*, Sul JH*, Tsetsos F* … Paschou P, Coppola G, Mathews CA§, Scharf JM§, and the Tourette Association of America International Consortium for Genetics, the Gilles de la Tourette Syndrome GWAS Replication Initiative, the Tourette International Collaborative Genetics Study, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group. Interrogating the genetic determinants of TS and other tic disorders through genome-wide association studies. American Journal of Psychiatry. 2019 Mar 1; 176(3): 27-227doi: 0.1176/appi.ajp.2018.18070857.
*Co-first author; §Co-senior author
Commentary. Ronald A. Common (genetic) links between clinics and the community: new evidence from a Tourette syndrome polygenic score. Biological Psychiatry 2019 Feb 15; 85(4): 281-282.
Abdulkadir M, Mathews CA, Scharf JM, Yu D, Tischfield JA, Heiman GA, Hoekstra PJ, Dietrich A. Polygenic Risk Scores Derived From a Tourette Syndrome Genome-wide Association Study Predict Presence of Tics in the Avon Longitudinal Study of Parents and Children Cohort. Biological Psychiatry. 2018 Sep 29. doi: 10.1016/j.biopsych.2018.09.011.
Wang S, Mandell JD, Kumar Y, Sun N, Morris MT, Arbelaez J, Nasello C, Dong S, Duhn C, Zhao X, Yang Z, Padmanabhuni SS, Yu D, King RA, Dietrich A, Khalifa N, Dahl N, Huang AY, Neale BM, Coppola G, Mathews CA, Scharf JM; Tourette International Collaborative Genetics Study (TIC Genetics); Tourette Syndrome Genetics Southern and Eastern Europe Initiative (TSGENESEE); Tourette Association of America International Consortium for Genetics (TAAICG), Fernandez TV, Buxbaum JD, De Rubeis S, Grice DE, Xing J, Heiman GA, Tischfield JA, Paschou P, Willsey AJ, State MW. De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis. Cell Reports. 2018 Sep 25;24(13):3441-3454.e12.doi: 10.1016/j.celrep.2018.08.082
Yilmaz Z, Halvorsen M, Bryois J, Yu D, Thornton LM, Zerwas S, Micali N, Moessner R, Burton CL, Zai G, Erdman L, Kas MJ, Arnold PD, Davis LK, Knowles JA, Breen G, Scharf JM, Nestadt G, Mathews CA, Bulik CM, Mattheisen M, Crowley JJ; Eating Disorders Working Group of the Psychiatric Genomics Consortium, Tourette Syndrome/Obsessive–Compulsive Disorder Working Group of the Psychiatric Genomics Consortium. Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder. Molecular Psychiatry. 2018 Aug 7. doi: 10.1038/s41380-018-0115-4.
Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B … Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM, Schott JM, Anney R, Elia J, Grigoroiu-Serbanescu M, Edenberg HJ, Murray R. Analysis of shared heritability in common disorders of the brain. Science. 2018 Jun 22;360(6395). pii: eaap8757.doi: 10.1126/science.aap8757.
Greenberg E, Tung ES, Gauvin C, Osiecki L, Yang KG, Curley E, Essa A, Illmann C, Sandor P, Dion Y, Lyon GJ, King RA, Darrow S, Hirschtritt ME, Budman CL, Grados M, Pauls DL, Keuthen NJ, Mathews CA, Scharf JM. Prevalence and predictors of hair pulling disorder and excoriation disorder in Tourette syndrome. European Child and Adolescent Psychiatry. 2018 May; 27(5): 569-579. doi: 10.1007/s00787-017-1074-z.
International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS) (including Scharf JM). Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis. Molecular Psychiatry. 2018 May; 23(5): 1181-1188. Aug 1. doi: 10.1038/mp.2017.154.
